Theoretically it doesn't really hurt so long as you use the proper equipment on your ship; that is, you don't try to run T1's on your Yorktown. But as a general rule of thumb, having better crews than your BO reduces the temptation of doing as such.
You may also want to raise at least one more fighter and a few DB pilots for flexibility. There's nothing wrong with having four fighter pilots, but raising more than that gives you tactical flexibility since you can swap your setup around whenever you want; run fighter-heavy and keep the enemy team blind, or bomber-heavy and kill ships, or whatever.
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